Upper Gastrointestinal Tract Associated Lesions in Patients with Newly Diagnosed Celiac Disease

(1) Background: Currently available guidelines require upper gastrointestinal (GI) endoscopy with biopsy sampling for adult celiac disease (CD) diagnosis. Based on the pediatric experience, there has been a growing interest if serology-based diagnosis would be possible CD also. Our aim was to analyze associated GI tract lesions in newly diagnosed patients, see significant pathology is detected during index endoscopy, which might impact patient management not related CD. (2) Methods: We performed retrospective analysis of cases over period 7 years (2014–2020). Demographic, clinical, laboratory, and histopathology data were collected from patients’ charts. Diagnosis set according ACG Guideline 2013. (3) Results: Altogether 79 patients recruited this study purpose, 75.9% female, median age 39 years. All had positive CD-specific serology atrophic mucosal injury duodenal samples. Besides villous atrophy, endoscopic findings 42/79 (53.16%) patients. Most gastric minor findings—small sliding hiatal hernias, non-specific chronic gastritis, but we also found two peptic ulcers, one case metaplastic six gastritis subepithelial lesion. Only changes duodenum except CD-related findings—an inflammatory polyp bulb. No malignancies found. (4) Conclusions: In our cohort, number who most them findings.